Benzene induces rapid leukemic transformation after prolonged hematotoxicity in a murine model

Signatures of mutational processes in human cancer

Ludmil B. Alexandrov, Serena Nik‐Zainal, David C. Wedge et al. · Nature · 2013 · 10.1K citations · Full text

Medicine, Cancer Biology, Oncology +14

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Giulio Genovese, Anna K. Kähler, Robert E. Handsaker et al. · New England Journal of Medicine · 2014 · 3.5K citations · Full text

Medicine, Genetics, Molecular Genetics +16

Chromosome translocations and covert leukemic clones are generated during normal fetal development

Hiroshi Mori, Susan Colman, Zhijian Xiao et al. · Proceedings of the National Academy of Sciences · 2002 · 612 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Detectable clonal mosaicism from birth to old age and its relationship to cancer

Cathy C. Laurie, Cecelia Laurie, Kenneth Rice et al. · Nature Genetics · 2012 · 599 citations · Full text

Medicine, Cancer Biology, Oncology +14

Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C-->T mutation and rapid fractional excretion of chlorzoxazone.

Nathaniel Rothman, Martyn T. Smith, Richard B. Hayes et al. · PubMed · 1997 · 274 citations

Pharmacy, Hematology, Toxicology +16