medRxiv · 2020 · 31 citations · 32 references
Veterinary MedicineInfectious DiseasesSpatial EpidemiologySpatial ModelingSpatial StatisticsEpidemic Curve AnalysisEpidemic ForecastingInfectious Disease DynamicsPopulation Dynamics ModelingPopulation MobilityTransmission DynamicsModeling Of Outbreak SpreadSpatial Disease DynamicsSpatial Epidemiology ModelingSpatial Transmission DynamicsSpatial-temporal Disease Modeling
Abstract Hawkes processes are used in machine learning for event clustering and causal inference, while they also can be viewed as stochastic versions of popular compartmental models used in epidemiology. Here we show how to develop accurate models of COVID-19 transmission using Hawkes processes with spatial-temporal covariates. We model the conditional intensity of new COVID-19 cases and deaths in the U.S. at the county level, estimating the dynamic reproduction number of the virus within an EM algorithm through a regression on Google mobility indices and demographic covariates in the maximization step. We validate the approach on short-term forecasting tasks, showing that the Hawkes process outperforms several benchmark models currently used to track the pandemic, including an ensemble approach and a SEIR-variant. We also investigate which covariates and mobility indices are most important for building forecasts of COVID-19 in the U.S.
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Neil M. Ferguson, Daniel J. Laydon, G Nedjati Gilani et al. · Spiral (Imperial College London) · 2020 · 3.8K citations · Full text
Medicine, Infectious Disease Control, Infectious Diseases +13
Stephen Eubank, Irene Eckstrand, Bryan Lewis et al. · Bulletin of Mathematical Biology · 2020 · 947 citations · Full text
Public Affairs, Health Policy, Infectious Disease Control +15