Concepedia

Metformin protects against ischaemic myocardial injury by alleviating autophagy-ROS-NLRP3-mediated inflammatory response in macrophages

Fei Qin, Heng Ma, Jiang Zou, Wenmei Wang, Huafei Deng, Meng Meng, Sipin Tan, Huali Zhang, Xianzhong Xiao, Nian Wang,

Journal of Molecular and Cellular Cardiology · 2020 · 132 citations · 36 references

DOI

Concepts

References

36

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Metformin and reduced risk of cancer in diabetic patients

Josie Evans, Louise A. Donnelly, Alistair Emslie‐Smith et al. · BMJ · 2005 · 2.4K citations · Full text

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Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

Kenichi Shimada, Timothy R. Crother, Justin N. Karlin et al. · Immunity · 2012 · 2.2K citations · Full text

, , +14

Network organization of the human autophagy system

Christian Behrends, Mathew E. Sowa, Steven P. Gygi et al. · Nature · 2010 · 1.6K citations · Full text

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SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

So Ra Kim, Sang‐Guk Lee, Soo Hyun Kim et al. · Nature Communications · 2020 · 515 citations · Full text

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