Morphological change and characteristics of myofibroblasts during the growth process of benign prostatic hyperplasia

Abstract

Differentiation into myofibroblasts induced by transforming growth factor-β1 and insulin-like growth factor-binding protein 3 actively occurs during the growth process of benign prostatic hyperplasia. Myofibroblast progenitor cells seem to be associated with prostatic fibrosis in human benign prostatic hyperplasia.