Journal of Clinical Microbiology · 2020 · 54 citations · 21 references
MedicineInfectious DiseasesDiagnostic MicrobiologyMedical MicrobiologyNeuroinfectious DiseasesCentral Nervous System InfectionsDiagnostic StewardshipEncephalitisInfectious Disease DetectionInfectious Disease ScreeningMicroscopic ExaminationCerebrospinal Fluid AnalysisCerebrospinal Fluid DiagnosisCerebrospinal Fluid DiagnosticsCohort Study InvestigationCryptococcal Antigen ScreeningCryptococcal MeningitisEncephalitis DiagnosisMeningitis Diagnosis
The impact of diagnostic stewardship and testing algorithms on the utilization and performance of the FilmArray meningitis/encephalitis (ME) panel has received limited investigation. We performed a retrospective single-center cohort study assessing all individuals with suspected ME between February 2017 and April 2019 for whom the ME panel was ordered. Testing was restricted to patients with cerebrospinal fluid (CSF) pleocytosis. Positive ME panel results were confirmed before reporting through correlation with direct staining (Gram and calcofluor white) and CSF cryptococcal antigen or by repeat ME panel testing.
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Amy L. Leber, Kathy Everhart, Joan‐Miquel Balada‐Llasat et al. · Journal of Clinical Microbiology · 2016 · 606 citations · Full text