Acta Clinica Belgica · 1998 · 14 citations · 0 references
MedicineHematologyInternal MedicineEarly DetectionHemostasisVascular SurgeryAnticoagulant TherapyDeep Vein ThrombosisThromboembolic DiseaseThrombosisVenous DiseaseVenous ThromboembolismDeep Vein Thrombosis AssessmentDeep Vein Thrombosis DetectionDeep Vein Thrombosis EvaluationDistal Deep Vein ThrombosisProximal Deep Vein ThrombosisVenous Thromboembolism AssessmentVenous Thromboembolism DetectionVenous Thromboembolism Diagnosis
A qualitative (Instantia) and a quantitative (VIDAS D-Dimer) D-Dimer test have been evaluated and compared with an ELISA method (Asserachrom D-D) in a population of 74 patients suspected of presenting a deep vein thrombosis. Among the thirty-two patients presenting a deep vein thrombosis on phlebography, there were 16 (50%) proximal vein thrombosis and 16 (50%) distal vein thrombosis. Sensitivity and negative predictive value for proximal thrombosis were 100% in all three tests. For distal vein thrombosis, sensitivity and negative predictive value were respectively 81% and 81% for Asserachrom D-DI 75% and 76% for VIDAS D-Dimer and 63% and 82% for Instantia. In conclusion, this study shows that these D-Di assays are a useful tool to exclude proximal vein thrombosis, at least for patients who are not under anticoagulant therapy.