Rapid and precise diagnosis of <i>T. marneffei</i> pulmonary infection in a HIV-negative patient with autosomal-dominant <i>STAT3</i> mutation: a case report

Abstract

In clinical practice, <i>T. marneffei</i> infection among HIV-negative individuals is relatively rare, and we found that patients who are congenitally immunocompromised due to <i>STAT3</i> mutation may be potential hosts. Early diagnosis and timely treatment are expected to improve the prognosis of <i>T. marneffei</i> infection. NGS is a powerful technique that may play an important role in this progress. <i>The reviews of this paper are available via the supplemental material section</i>.