Concepedia

Cannabinoid CP55940 selectively induces apoptosis in Jurkat cells and in ex vivo T-cell acute lymphoblastic leukemia through H2O2 signaling mechanism

Viviana Soto‐Mercado, Miguel Mendivil‐Perez, Marlene Jiménez-Del-Río, Javier E. Fox, Carlos Velez‐Pardo

Leukemia Research · 2020 · 30 citations · 29 references

DOI

Concepts

References

29

PUMA, a Novel Proapoptotic Gene, Is Induced by p53

Katsunori Nakano, Karen H. Vousden · Molecular Cell · 2001 · 2.3K citations · Full text

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Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis

Reiner U. Jänicke, Michael L. Sprengart, Mas Rina Wati et al. · Journal of Biological Chemistry · 1998 · 2K citations · Full text

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

Noriyuki Matsuda, Shigeto Sato, Kahori Shiba et al. · The Journal of Cell Biology · 2010 · 1.9K citations · Full text

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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang et al. · Open Biology · 2012 · 944 citations · Full text

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Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

Agne Kazlauskaite, Chandana Kondapalli, Robert Gourlay et al. · Biochemical Journal · 2014 · 815 citations · Full text

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