Concepedia

Publication | Open Access

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

DOIFull Paper Access

214

Citations

38

References

2020

Year

Wungki Park, Jiapeng Chen, Joanne F. Chou, Anna M. Varghese, Kenneth H. Yu, Winston Wong, Marinela Capanu, Vinod P. Balachandran, Caitlin A. McIntyre, Imane El Dika,
Clinical Cancer Research

Abstract

Pathogenic HRm identifies HRD in patients with PDAC with the best outcome when treated with 1L-platinum. Biallelic HRm and core HRm further enriched benefit from 1L-platinum from HRD.

References

YearCitations

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