The influence of delivery rate of whole body 250 kv. roentgen irradiation (30 or 3 roentgens per minute) on mice, rats and guinea pigs.

Abstract

Mice, rats, and guinea pigs were given whole-body roentgen irradiation with 250 kv at rates of 30 r/min and 3 r/min. The rat showed the most tolerance to low-rate roentgen irradiation with an increase of 38 per cent in the LD/sub 50/ 30/; the mouse LD/sub 50/30/ increased 14 per cent; the guinea pig was equally sensitive regardless of rate. This difference in response cannot be ascribed to accepted acute recovery rates for these species. (auth)