Publication | Closed Access
Design, synthesis, and biological evaluation of novel nicotinamide derivatives as potential histone deacetylase-3 inhibitors
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Citations
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References
2020
Year
Pharmaceutical SciencePharmacotherapyChemical BiologyMolecular PharmacologyMedicinal ChemistrySelectivity Towards Hdac3ToxicologyBiological EvaluationNovel Nicotinamide DerivativesAnti-cancer AgentInhibitory ActivityBiochemistryCell LinesPharmacological AgentDrug DevelopmentPharmacologyPan HdacNatural SciencesMedicineDrug Discovery
The selected nicotinamide-based HDAC<italic>i</italic> displayed selectivity towards HDAC3 over pan HDAC and exhibited potent cytotoxicity against the used cell lines.
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