Fasudil alleviates hepatic fibrosis in type 1 diabetic rats: involvement of the inflammation and RhoA/ROCK pathway.

Yang Xie, Tengwei Song, Huo M, Y Zhang, YY Zhang, Ma Zh, N Wang, Zhang Jp

PubMed · 2018 · 24 citations · 0 references

Abstract

These results suggest that fasudil exert anti-inflammation actions and markedly decrease the accumulation of extracellular matrix. Fasudil is a good candidate agent for treating hepatic fibrosis in diabetes.