Synthesis of (1‐substituted piperidin‐4‐yl)‐1<i>H</i>‐benzimidazoles and (1‐substituted piperidin‐4‐yl)‐3,4‐dihydroquinazolines as possible antihypertensive agents

Abstract

Abstract Structural modifications of 4‐piperidylbenzimidazolinones (I) by replacing the benzimidazolinone group with other heterocycles (2‐cyanoamino, 2‐ethoxy, and 2‐methylbenzimidazole and 2‐cyanoamino‐3,4‐dihydroquinazoline) has been made and a number of new piperidines (II) were synthesized as potential antihypertensive agents.