Concepedia

Combination dose-escalated hydroxyurea and transfusion: an approach to conserve blood during the COVID-19 pandemic

Robert Sheppard Nickel, Stefanie Margulies, Brittany Frazer, Naomi L.C. Luban, Jennifer Webb

Blood · 2020 · 14 citations · 19 references

DOIFull text

Open access

Concepts

Abstract

Nickel et al describe a single-arm trial using dose-escalated hydroxyurea and regular transfusions to prevent complications of sickle cell anemia. Preliminary results suggest that a reduction in volume of red cell requirements may be achievable.

References

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