Concepedia

Design and Development of an HBT-Based Ratiometric Fluorescent Probe to Monitor Stress-Induced Premature Senescence

Juliann Nzembi Makau, Ayako Kitagawa, Kanami Kitamura, Tomoko Yamaguchi, Satoshi Mizuta

ACS Omega · 2020 · 16 citations · 21 references

DOIFull text

Open access

Concepts

Abstract

-treated HeLa cells. Furthermore, these probes were successfully employed for imaging the increased levels of ROS and β-galactosidase activity in the doxorubicin-treated HeLa cells.

References

21

Senescence‐associated β‐galactosidase is lysosomal β‐galactosidase

Bo Yun Lee, Jung A Han, Jun Sub Im et al. · Aging Cell · 2006 · 1.4K citations · Full text

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Senescence-associated β-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells

David J. Kurz, Stéphanie Decary, Ying Hong et al. · Journal of Cell Science · 2000 · 859 citations

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Boronate Oxidation as a Bioorthogonal Reaction Approach for Studying the Chemistry of Hydrogen Peroxide in Living Systems

Alexander R. Lippert, Genevieve C. Van de Bittner, Christopher J. Chang · Accounts of Chemical Research · 2011 · 795 citations · Full text

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An ICT-Based Approach to Ratiometric Fluorescence Imaging of Hydrogen Peroxide Produced in Living Cells

Duangkhae Srikun, Evan W. Miller, Dylan W. Domaille et al. · Journal of the American Chemical Society · 2008 · 540 citations

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β-Galactosidase Fluorescence Probe with Improved Cellular Accumulation Based on a Spirocyclized Rhodol Scaffold

Mako Kamiya, Daisuke Asanuma, Erina Kuranaga et al. · Journal of the American Chemical Society · 2011 · 239 citations

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