Concepedia

Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients

Luca F. Roggeveen, Tingjie Guo, Ronald H. Driessen, Lucas M. Fleuren, Patrick Thoral, Peter H. J. van der Voort, Armand R. J. Girbes, Rob J. Bosman, Paul Elbers

Frontiers in Pharmacology · 2020 · 28 citations · 28 references

DOIFull text

Open access

Abstract

We successfully developed a CDSS for real time model informed precision antibiotic dosing at the bedside of the critically ill. This holds great promise for improving sepsis outcome. Therefore, we recently started the Right Dose Right Now multi-center randomized control trial to validate this concept in 420 patients with severe sepsis and septic shock.

References

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