Emerging infectious diseases · 2020 · 146 citations · 11 references
Veterinary MedicineInfectious DiseasesPathologyAutopsy PathologyPulmonologyVirologyPulmonary PathologyRespiratory DiseaseRespiratory InfectionsRespiratory Infectious DiseasesRespiratory PathologyViral InfectionsImmunohistochemical DetectionImmunohistochemical MarkersImmunohistochemical StainingPneumonia PathologyRespiratory Viral InfectionsRespiratory Viral PathogenesisSevere Acute Respiratory SyndromeViral Respiratory Infections
C oronavirus disease (COVID-19), which was first reported in December 2019 in Wuhan, China, has been spreading rapidly and on a global scale. The causative virus is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (1). The World Health Organization declared the outbreak of COVID-19 to be pandemic on March 11, 2020, and had reported 693,282 laboratory-confirmed cases and 33,106 deaths globally as of March 30 (2). Numerous studies of the clinical features of COVID-19 and the virologic characteristics of SARS-CoV-2 have been conducted in China to date Postmortem examination will provide valuable information required to elucidate the pathogenesis of COVID-19; however, only 2 studies have been published on COVID-19 pathology thus far (5,6). Further, the distribution of SARS-CoV-2 in a patient and identification of which cells are infected by SARS-CoV-2 have yet to be reported.
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