Quadruple therapy for asymptomatic COVID-19 infection patients

Abstract

The two asymptomatic patients far away from Wuhan did not seem to be highly contagious. They improved obviously, after treatment with the quadruple therapy, but the effective drug is still unknown. It should be noted that lopinavir/ritonavir tablets have many drug interactions and are the most likely drugs to cause hyperlipidemia and hyperglycemia in these two patients. IFN-α2b is more effective in the early stage of virus infection. Arbidol instruction dose may not be sufficient to inhibit the novel coronavirus <i>in vivo</i>. The evidence-based medicine of Lianhuaqingwen granules for treating various viral infections is just based on Chinese patients.