IEEE Access · 2020 · 22 citations · 25 references
MedicinePharmacologyDrug InformationMachine LearningPharmacoinformaticsAdverse Drug Reaction PredictionDeep LearningDrug Knowledge RepresentationNetwork PharmacologyNeural NetworksPharmaceutical Knowledge RepresentationSide Effect Network AnalysisSide Effect PredictionTraditional Chinese Medicine
In this paper, we realize high-accuracy side-effect prediction of Traditional Chinese Medicine Compound Prescription by introducing network embedding and deep learning. A random walk network that could efficiently interpret the information in the prescription is established from a conventional Bag-of-Word network. After the validation of this random walk network, the highest prediction accuracy reaches 0.908 where a simple five-layer artificial neural network is implemented, rendering this method is promising for Traditional Chinese Medicine side-effect prediction and other medicines with a similar structure such as the compound drugs.
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Aristolochic acid-associated urothelial cancer in Taiwan
Chung‐Hsin Chen, Kathleen G. Dickman, Masaaki Moriya et al. · Proceedings of the National Academy of Sciences · 2012 · 414 citations · Full text