Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19. - Concepedia

Concepedia

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Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19.

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References

2020

Year

Savino Sciascia, Franco Aprà, Alessandra Baffa, Simone Baldovino, Daniela Boaro, R Boero, Stefano Bonora, Andrea Calcagno, Irene Cecchi, Giacoma Cinnirella,

Abstract

In hospitalised adult patients with severe COVID-19, TCZ could be a safe option. An improvement in respiratory and laboratory parameters was observed. Future controlled trials in patients with severe illness are urgently needed to confirm the definite benefit with IL-6 target therapy.