Computer Methods in Biomechanics & Biomedical Engineering · 2020 · 344 citations · 21 references
Public HealthInfectious Disease ControlInfectious DiseasesEpidemiologic MethodsEpidemiologyInfectious Disease EpidemiologyDisease SpreadEpidemic ForecastingOutbreak ControlPandemic ResponseTravel-associated InfectionsTravel-related Infectious DiseasesDisease Outbreak DynamicsDisease Outbreak ForecastingMobility During Public Health EmergenciesMobility-based Transmission ModelingPandemic Spread PatternsPopulation Outbreak DynamicsTravel-associated SpreadTravel-associated Transmission
For the first time in history, on March 17, 2020, the European Union closed all its external borders in an attempt to contain the spreading of the coronavirus 2019, COVID-19. Throughout two past months, governments around the world have implemented massive travel restrictions and border control to mitigate the outbreak of this global pandemic. However, the precise effects of travel restrictions on the outbreak dynamics of COVID-19 remain unknown. Here we combine a global network mobility model with a local epidemiology model to simulate and predict the outbreak dynamics and outbreak control of COVID-19 across Europe. We correlate our mobility model to passenger air travel statistics and calibrate our epidemiology model using the number of reported COVID-19 cases for each country. Our simulations show that mobility networks of air travel can predict the emerging global diffusion pattern of a pandemic at the early stages of the outbreak. Our results suggest that an unconstrained mobility would have significantly accelerated the spreading of COVID-19, especially in Central Europe, Spain, and France. Ultimately, our network epidemiology model can inform political decision making and help identify exit strategies from current travel restrictions and total lockdown.
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The Mathematics of Infectious Diseases
Herbert W. Hethcote · SIAM Review · 2000 · 6.9K citations
Epidemic processes in complex networks
Romualdo Pastor‐Satorras, Claudio Castellano, Piet Van Mieghem et al. · Reviews of Modern Physics · 2015 · 3.7K citations · Full text
Veterinary Medicine, Infectious Diseases, Biological Systems Modeling +16
Kiesha Prem, Yang Liu, Timothy Russell et al. · The Lancet Public Health · 2020 · 2.3K citations · Full text
Veterinary Medicine, Infectious Disease Control, Infectious Diseases +17