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<p>Circ-OXCT1 Suppresses Gastric Cancer EMT and Metastasis by Attenuating TGF-β Pathway Through the Circ-OXCT1/miR-136/SMAD4 Axis</p>

Jianjun Liu, Xinglong Dai, Xiong Guo, Anqi Cheng, Sandrie Mariella Mac, Ziwei Wang

OncoTargets and Therapy · 2020 · 38 citations · 25 references

DOIFull text

Open access

Abstract

Our data showed that circ-OXCT1 suppresses gastric cancer EMT and metastasis through TGF-β/Smad signaling pathway. The clinicopathologic data analysis revealed that circ-OXCT1 overexpression could be a novel treatment for advanced GC especially with distant metastasis by targeting the circ-OXCT1/miR-136/SMAD4 axis.

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