NHC-catalyzed β-specific addition of N-based nucleophiles to allenoates

Abstract

N-heterocyclic carbene (NHC) catalyzed reactions of nitrogenous heterocycles or trifluoromethylated acylhydrazone with allenoates gave regiospecific β-adducts. DFT calculations rationalized the origination of regio- and <italic>E</italic>/<italic>Z</italic> selectivities.