Journal of Clinical Microbiology · 2020 · 271 citations · 29 references
PharmacyClinical SciencesInfectious DiseasesAntimicrobial StewardshipDiagnostic MicrobiologyMedical MicrobiologyDiagnostic StewardshipHospital Antimicrobial StewardshipPathogen DetectionRespiratory InfectionsRespiratory Pathogen DiagnosticsRespiratory Tract InfectionsAntimicrobial Stewardship EvaluationCausative PathogensInfection Risk FactorsInfectious EtiologyPneumonia DiagnosisPneumonia Severity AssessmentSeverity AssessmentVentilator-associated Pneumonia
genomic copies/ml by the PN panel. Viral targets were identified by the PN panel in 17.7% of specimens tested, of which 39.1% were detected in conjunction with a bacterial target. A review of patient medical records, including clinically prescribed antibiotics, revealed the potential for antibiotic adjustment in 70.7% of patients based on the PN panel result, including discontinuation or de-escalation in 48.2% of patients, resulting in an average savings of 6.2 antibiotic days/patient.
29
André C. Kalil, Mark L. Metersky, Michael Klompas et al. · Clinical Infectious Diseases · 2016 · 3.9K citations · Full text
Antoní Torres, Michael S. Niederman, Jean Chastre et al. · European Respiratory Journal · 2017 · 1.4K citations · Full text
Matthew J. Binnicker, Sheldon Campbell, Karen C. Carroll et al. · Clinical Infectious Diseases · 2018 · 458 citations