First-in-Human Assessment of cRGD-ZW800-1, a Zwitterionic, Integrin-Targeted, Near-Infrared Fluorescent Peptide in Colon Carcinoma - Concepedia

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First-in-Human Assessment of cRGD-ZW800-1, a Zwitterionic, Integrin-Targeted, Near-Infrared Fluorescent Peptide in Colon Carcinoma

100

Citations

32

References

2020

Year

Kim S. de Valk, Marion M. Deken, Henricus J.M. Handgraaf, Shadhvi S. Bhairosingh, Okker D. Bijlstra, Michiel J. van Esdonk, Anton G.T. Terwisscha van Scheltinga, A. Rob P.M. Valentijn, Taryn L. March, Jaap Vuijk,

Clinical Cancer Research

Abstract

cRGD-ZW800-1 enabled fluorescence imaging of colon cancer in both open and minimal invasive surgeries. Further development of cRGD-ZW800-1 for widespread use in cancer surgery may be warranted given the ubiquitous overexpression of various integrins on different types of tumors and their vasculature.

References

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