H9N2 avian influenza virus retained low pathogenicity after serial passage in chickens.

Akinlolu Jegede, Qigao Fu, Yohannes Berhane, Min Lin, Ashok Kumar, Jiewen Guan

PubMed · 2018 · 14 citations · 32 references

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Abstract

< 0.05) less thermostable than P0. Collectively, after 19 passages in chickens the H9N2 AIVs retained low pathogenicity with a positive selection of L226 in the HA. These findings suggest that H9N2 viruses might acquire mammalian specificity after asymptomatic circulation in avian species.

References

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