Relationship between intestinal flora structure and metabolite analysis and immunotherapy efficacy in Chinese <scp>NSCLC</scp> patients

Abstract

We found a close correlation between intestinal microbiome β-diversity and anti-PD-1 immunotherapy response in Chinese patients with advanced NSCLC. The intestinal flora composition, functional group protein family, and KEGG metabolism also differed between the two groups. Differences in pathways and flora metabolites were also noted.