Pro-Oxidant Therapeutic Activities of Cerium Oxide Nanoparticles in Colorectal Carcinoma Cells

Aparna Datta, Snehasis Mishra, Krishnendu Manna, Krishna Das Saha, Siddhartha Mukherjee, Somenath Roy

ACS Omega · 2020 · 124 citations · 32 references

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Abstract

treatment causes DNA fragmentation through enhanced generation of ROS, which ultimately leads to cellular apoptosis through the p53-dependent mitochondrial signaling pathway.

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