Concepedia

Genetic Analysis of Invasive Pneumococcal Isolates from Children in Ontario, Canada, 2007–2012

Xianding Deng, Gitanjali Arya, Nader Memari, Ronald A. MacKenzie, Gregory MacMullin, Donald E. Low, Dylan R. Pillai, Jonathan B. Gubbay

The Pediatric Infectious Disease Journal · 2015 · 15 citations · 17 references

DOI

Abstract

Genetic shift because of PCV13 impact may have resulted in the decline of 19A in IPD. Recent rise of serogroup 15 infections in children could be because of its selective advantage conferred by genetic diversity, frequent recombination in the population plus drug resistance potential related to CC63 genotype. Close monitoring of serotype replacement and genetic change in IPD among children post-PCV13 is warranted.

References

17

Multilocus sequence typing: A portable approach to the identification of clones within populations of pathogenic microorganisms

Martin Maiden, Jane A. Bygraves, Edward J. Feil et al. · Proceedings of the National Academy of Sciences · 1998 · 3.8K citations

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Sustained Reductions in Invasive Pneumococcal Disease in the Era of Conjugate Vaccine

Tamara Pilishvili, Catherine Lexau, Monica M. Farley et al. · The Journal of Infectious Diseases · 2009 · 1.3K citations · Full text

Incidence of Pneumococcal Disease Due to Non–Pneumococcal Conjugate Vaccine (PCV7) Serotypes in the United States during the Era of Widespread PCV7 Vaccination, 1998–2004

Lauri A. Hicks, Lee H. Harrison, Brendan Flannery et al. · The Journal of Infectious Diseases · 2007 · 742 citations · Full text

Clonal Relationships between Invasive and Carriage<i>Streptococcus pneumoniae</i>and Serotype‐ and Clone‐Specific Differences in Invasive Disease Potential

Angela B. Brueggemann, David Griffiths, Emma Meats et al. · The Journal of Infectious Diseases · 2003 · 628 citations · Full text

Human Metapneumovirus Infections in Young and Elderly Adults

Ann R. Falsey, Dean D. Erdman, Larry J. Anderson et al. · The Journal of Infectious Diseases · 2003 · 597 citations · Full text