medRxiv · 2020 · 55 citations · 16 references
ComputingBiostatisticsInfectious DiseasesDynamical SystemsMachine LearningStatistical ModelingDeep LearningDisease ModelingInfectious Disease DynamicsNeural NetworksNumerical Methods For Differential EquationsPopulation Dynamics ModelingBasic Reproduction Number EstimationEpidemic ModelsInfectious Disease ModelsMathematical Modeling Of EpidemicsMathematical Modeling Of Viral SpreadModeling Of Outbreak SpreadReproduction Number AnalysisTime-varying Parameters
Abstract Mathematical modeling is a process aimed at finding a mathematical description of a system and translating it into a relational expression. When a system is continuously changing over time (e.g., infectious diseases) differential equations, which may include parameters, are used for modeling the system. The process of finding those parameters that best fit the given data from the system is called an inverse problem. This study aims at analyzing the novel coronavirus infection (COVID-19) spread in South Korea using the susceptible-infected-recovered (SIR) model. We collect the data from Korea Centers for Disease Control & Prevention (KCDC). We assume that each parameter in the SIR model is a function of time so that we can compute important parameters, such as the basic reproduction number (R0), more delicately. Using neural networks, we propose a method to find the best time-varying parameters and the solution for the model simultaneously. Moreover, using time-dependent parameters, we find that traditional numerical algorithms, such as the Runge-Kutta methods, can successfully approximate the SIR model while fitting the COVID-19 data, thus modeling the propagation patterns of COVID-19 more precisely.
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Multilayer feedforward networks are universal approximators
Kurt Hornik, Maxwell B. Stinchcombe, Halbert White · Neural Networks · 1989 · 21.2K citations
Maziar Raissi, Paris Perdikaris, George Em Karniadakis · Journal of Computational Physics · 2018 · 16.9K citations · Full text
Multilayer feedforward networks are universal approximators
HornikK., StinchcombeM., WhiteH. · Neural Networks · 1989 · 9.4K citations