Cortical morphological changes in chronic migraine in a Taiwanese cohort: Surface- and voxel-based analyses

Abstract

Patients with chronic migraine without medication overuse headache, major depression, or prior preventive treatment had reduced cortical thickness in regions within the pain-processing network. Compared to voxel-based morphometry, surface-based morphometry analysis may be more sensitive to subtle structural differences between healthy controls and patients with chronic migraine.