Concepedia

<i>O</i> -GlcNAc transferase promotes influenza A virus–induced cytokine storm by targeting interferon regulatory factor–5

Qiming Wang, Rui He, Mengqi Li, Haisheng Yu, Li Zhou, Yi Yu, Fubing Wang, Yi Zhang, Aidong Chen, Nanfang Peng,

Science Advances · 2020 · 120 citations · 27 references

DOIFull text

Open access

Concepts

Abstract

-GlcNAcylation regulates IRF5 function during IAV infection, highlighting the importance of glucose metabolism in IAV-induced cytokine storm.

References

27

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

Almut Brand, Katrin Singer, Gudrun E. Koehl et al. · Cell Metabolism · 2016 · 1.9K citations · Full text

, , +12

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

Bart Everts, Eyal Amiel, Stanley Ching‐Cheng Huang et al. · Nature Immunology · 2014 · 1K citations · Full text

, , +16

Increased Risk of Common Infections in Patients with Type 1 and Type 2 Diabetes Mellitus

L M A J Muller, K. J. Gorter, Eelko Hak et al. · Clinical Infectious Diseases · 2005 · 1K citations · Full text

, , +17

The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

Raheel Shafi, Sai Prasad N. Iyer, Lesley G. Ellies et al. · Proceedings of the National Academy of Sciences · 2000 · 795 citations

, , +15

Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation

Andrew Wang, Sarah C. Huen, Harding H. Luan et al. · Cell · 2016 · 592 citations · Full text

, , +14