Concepedia

A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity

Joanne A. Hammill, Jacek M. Kwiecień, Anna Dvorkin‐Gheva, Vivian Wing Chong Lau, Christopher L. Baker, Ying Wu, Ksenia Bezverbnaya, Craig Aarts, Christopher W. Heslen, Galina Denisova,

Molecular Therapy — Oncolytics · 2020 · 19 citations · 38 references

DOIFull text

Open access

Concepts

Abstract

CAR-T cell product, indicating a role for additional variables. This work highlights the contributions of CAR-T cell-intrinsic variables to the pathogenesis of off-tumor toxicity.

References

38

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