Concepedia

IL-6-targeted ultrasmall superparamagnetic iron oxide nanoparticles for optimized MRI detection of atherosclerotic vulnerable plaques in rabbits

Huaqiang Mo, Chenxing Fu, Zhiye Wu, Peng Liu, Zhibo Wen, Qingqing Hong, Yanbin Cai, Gongxin Li

RSC Advances · 2020 · 11 citations · 30 references

DOIFull text

Open access

Concepts

Abstract

Herein, we report Anti-IL-6-USPIO for detecting IL-6 in inflammatory macrophages and MR imaging vulnerable plaques of atherosclerosis in rabbit, which would provide a novel non-invasive strategy for evaluating acute cardiovascular risk or exploiting anti-atherosclerotic drugs.

References

30

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Zhenghuan Zhao, Zijian Zhou, Jianfeng Bao et al. · Nature Communications · 2013 · 475 citations · Full text

, , +16