Science Advances · 2020 · 83 citations · 30 references
DentistryOral BiologyPulp BiologyRegenerative MedicineStem Cell BiologyDental PulpPulp Cell BiologyPulp RepairPulp Stem CellsPulp-dentin ComplexTooth RegenerationDental Stem CellsDentin-pulp Complex RepairOsteogenic DifferentiationPulpal Tissue RegenerationRegenerative Pulp TherapySpheroid CultureSpheroid Culture ModelsThree-dimensional Cell Culture
cells could be detected in primary dental papilla in mice and human, suggesting that MDPSCs resided in their native niches. Together, our study has identified a previously unidentified group of multipotent pulp regenerative stem cells with defined molecular markers for the potential treatment of pulpitis and pulp necrosis.
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