Expressions of ezrin, <scp>ERK</scp>, <scp>STAT3</scp>, and <scp>AKT</scp> in tongue cancer and association with tumor characteristics and patient survival

Abstract

Ezrin, ERK, STAT3, and AKT appear to be involved in the progress from carcinoma in situ in the tongue into squamous cell carcinoma. ERK in particular is overexpressed, suggesting that ERK may be a novel therapeutic target for preventing tongue cancer.