Concepedia

Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease

Jun Kai, Yang Xiang, Zhimin Wang, Feixia Wang, Yan Jia, Shijun Wang, Shanzhong Tan, Anping Chen, Jiangjuan Shao, Zili Zhang,

Free Radical Biology and Medicine · 2020 · 106 citations · 42 references

DOI

Concepts

References

42

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu, Zhibin Zhang, Jianbin Ruan et al. · Nature · 2016 · 3.2K citations · Full text

, , +9

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

Adeline Bertola, Stephanie Mathews, Sung Hwan Ki et al. · Nature Protocols · 2013 · 1.2K citations · Full text

, , +12

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Alexander Wree, Akiko Eguchi, Matthew D. McGeough et al. · Hepatology · 2013 · 934 citations · Full text

, , +17

Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during <i>Yersinia</i> infection

Joseph Sarhan, Beiyun C. Liu, Hayley I. Muendlein et al. · Proceedings of the National Academy of Sciences · 2018 · 895 citations · Full text

, , +15