Concepedia

PACAP neuropeptide promotes Hepatocellular Protection via CREB-KLF4 dependent autophagy in mouse liver Ischemia Reperfusion Injury

Zhengze Xue, Yu Zhang, Yuanxing Liu, Cheng Zhang, Xiu‐Da Shen, Feng Gao, Ronald W. Busuttil, Shusen Zheng, Jerzy W. Kupiec‐Weglinski, Haofeng Ji

Theranostics · 2020 · 26 citations · 43 references

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Concepts

Abstract

: Current study documents the essential neural regulation of PACAP-promoted autophagy in hepatocellular homeostasis in OLT, which provides the emerging therapeutic principle to combat hepatic IRI in OLT.

References

43

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Autophagy in the Pathogenesis of Disease

Beth Levine, Guido Kroemer · Cell · 2008 · 7K citations · Full text

, , +10

Autophagy fights disease through cellular self-digestion

Noboru Mizushima, Beth Levine, Ana María Cuervo et al. · Nature · 2008 · 6.4K citations · Full text

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Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells

Atsuro Miyata, Akira Arimura, Raymond R. Dahl et al. · Biochemical and Biophysical Research Communications · 1989 · 1.8K citations

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Induction of Pluripotent Stem Cells From Adult Human Fibroblasts by Defined Factors

Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Obstetrical & Gynecological Survey · 2008 · 1.2K citations · Full text

, , +12