Correlation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn’s Disease Patients

Abstract

We included 159 patients (63 Crohn's disease with colonic involvement and 96 with ulcerative colitis). We found significant correlation between the Mayo endoscopic subscoring system and histology activity in ulcerative colitis, while no correlation was found in patients with Crohn's disease. Patient-reported outcome showed inverse correlation with endoscopic and histological activity in Crohn's disease (<i>r</i> _s = -0.67; <i>r</i> _s = -0.72), while positive correlation was found in ulcerative colitis (<i>r</i> _s = 0.84; <i>r</i> _s = 0.75). <i>Interpretation and Conclusions</i>. Patient-reported outcome is a practical and noninvasive tool for assessment of disease activity in ulcerative colitis patients but not in Crohn's disease.