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Publication | Open Access

Cancer Risk Stratification of Anal Intraepithelial Neoplasia in Human Immunodeficiency Virus–Positive Men by Validated Methylation Markers Associated With Progression to Cancer

DOIFull Paper Access

45

Citations

23

References

2020

Year

Ramon P van der Zee, Olivier Richel, Carel J.M. van Noesel, Iuliana Ciocănea‐Teodorescu, Annina P. van Splunter, Timo J. ter Braak, Mayura Nathan, Tamzin Cuming, Michael Sheaff, Alexander Kreuter,
Clinical Infectious Diseases

Abstract

We validated the accuracy of 5 methylation markers for the detection of anal (pre-) cancer. High methylation levels in HGAIN were associated with progression to cancer. These markers provide a promising tool to identify HGAIN in need of treatment, preventing overtreatment of HGAIN with a low cancer progression risk.

References

YearCitations

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