Concepedia

Direct synthesis of annulated indoles through palladium-catalyzed double alkylations

Yadong Gao, Jianhua Li, Songlin Bai, Daoquan Tu, Chao Yang, Zhiwen Ye, Bingcheng Hu, Xiangbing Qi, Chao Jiang

Organic Chemistry Frontiers · 2020 · 19 citations · 67 references

DOI

Concepts

Abstract

A facile, one-step synthesis of annulated indoles from (N–H) indoles and dibromoalkanes was developed through a palladium-catalyzed double alkylation process.

References

67

Catalytic Functionalization of Indoles in a New Dimension

Marco Bandini, Astrid Eichholzer · Angewandte Chemie International Edition · 2009 · 1.4K citations

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A Complex Catalytic Cycle Leading to a Regioselective Synthesis of <i>o,o</i>′‐Disubstituted Vinylarenes

Marta Catellani, Franco Frignani, Armando Rangoni · Angewandte Chemie International Edition in English · 1997 · 711 citations

, , +12

Pd/Norbornene: A Winning Combination for Selective Aromatic Functionalization via C–H Bond Activation

Nicola Della Ca’, Marco Fontana, Elena Motti et al. · Accounts of Chemical Research · 2016 · 648 citations

, , +12

Transient Directing Groups for Transformative C–H Activation by Synergistic Metal Catalysis

Parthasarathy Gandeepan, Lutz Ackermann · Chem · 2017 · 642 citations · Full text

, , +13

Ligand-enabled meta-C–H activation using a transient mediator

Xiaochen Wang, Wei Gong, Ru‐Yi Zhu et al. · Nature · 2015 · 593 citations · Full text

, , +7