CrystEngComm · 2020 · 27 citations · 37 references
Natural SciencesChemistryCrystal StructurePhysical ChemistrySolid-state ChemistryCrystal ChemistryCrystal SystemsCrystallization ProcessesCrystallographyMelting Behavior AnalysisPhase EquilibriaAqueous Solubility RelationshipChiral ThermodynamicsCocrystal FormationMelting PointMelting Point AnalysisMelting RelationsPackingPacking Efficiency
Comparison of chiral and racemic binary cocrystals showed that the chiral building block limits the formation of certain intermolecular interactions, decreases the packing efficiency, lowers the melting point and increases aqueous solubility.
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