Microemulsion-based approach for oral delivery of insulin: formulation design and characterization

Mumuni A. Momoh, Franklin Chimaobi Kenechukwu, Chinazom Precious Agbo, Calister E. Ugwu, Musiliu Adedokun, Ofomatah C. Anthony, Omeje E. Chidozie, Augustine N. Okorie

Heliyon · 2020 · 47 citations · 26 references

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Abstract

evaluations in diabetic rat model shows that insulin-loaded microencapsulation effectively reduced blood glucose levels over a period >8 h after oral administration. Therefore, we suggest that the developed formulation for oral insulin can be a promising alternative dosage form for oral protein delivery.

References

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