Single-nucleotide polymorphisms of <i>HLA</i> and <i>Polygonum multiflorum</i>-induced liver injury in the Han Chinese population

Abstract

BACKGROUND: -induced liver injury (PM-DILI). However, little is known about the relationship between single-nucleotide polymorphisms (SNPs) and PM-DILI. AIM: To identify SNPs that indicate susceptibility to PM-DILI. METHODS: after Bonferroni correction was considered significant. RESULTS: , OR = 62.62, 95%CI: 35.91-109.20) in the Han-MHC database. CONCLUSION: , rs1055348 may become an alternative predictive biomarker of PM-DILI.