Synthesis of Au@ZIF-8 nanocomposites for enhanced electrochemical detection of dopamine

Abstract

Gold nanoparticles and zeolitic imidazolate framework-8 nanocomposites ([email protected]) were synthesized through a simple hydrothermal method and used as an enzyme-free sensor for dopamine detection. Various characterizations were used to investigate the structure and morphology of [email protected] nanocomposites. The electrochemical performance of [email protected] nanocomposite modified glassy carbon electrode ([email protected]/GCE) was examined in 0.1 M phosphate-buffered saline with different concentrations of dopamine. Consequently, [email protected]/GCE possessed an excellent electrochemical catalytic performance to dopamine, having been reported to its wider linear range from 0.1 to 50 μM, lower detection limit of 0.01 μM (S/N = 3) and higher sensitivity of 6.452 μA mM−1 cm−2. The proposed sensor exhibited acceptable stability and repeatability due to the coupling effect of Au nanoparticles and ZIF-8. All the evidence suggested a potential application of [email protected] nanocomposites in a non-enzymatic dopamine sensor.