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Emergence of ceftazidime/avibactam resistance in KPC-8–producing Klebsiella pneumoniae in South America

Marcela Nastro, Daniela Cejas, Gemina Santana, M.B. Mancino, Mariana Hidalgo, Gustavo Maccallini, Carlos Vay, Marcela Rádice, Laura Dabos, Àngela Famiglietti,

Clinical Microbiology and Infection · 2020 · 16 citations · 7 references

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Emergence of Ceftazidime-Avibactam Resistance and Restoration of Carbapenem Susceptibility in Klebsiella pneumoniae Carbapenemase-Producing K pneumoniae: A Case Report and Review of Literature

Ryan K. Shields, M. Hong Nguyen, Ellen G. Press et al. · Open Forum Infectious Diseases · 2017 · 126 citations · Full text

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Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability

Shrenik Mehta, Kacie Rice, Timothy Palzkill · PLoS Pathogens · 2015 · 110 citations · Full text

, , +17

High ceftazidime hydrolysis activity and porin OmpK35 deficiency contribute to the decreased susceptibility to ceftazidime/avibactam in KPC-producing Klebsiella pneumoniae

Zhen Shen, Baixing Ding, Meiping Ye et al. · Journal of Antimicrobial Chemotherapy · 2017 · 108 citations · Full text

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Impaired Inhibition by Avibactam and Resistance to the Ceftazidime-Avibactam Combination Due to the D <sup>179</sup> Y Substitution in the KPC-2 β-Lactamase

Fabrice Compain, Michel Arthur · Antimicrobial Agents and Chemotherapy · 2017 · 98 citations · Full text

, , +16

Emergence of ceftazidime/avibactam resistance in KPC-3-producing Klebsiella pneumoniae in vivo

Stephan Göttig, Denia Frank, Eleonora Mungo et al. · Journal of Antimicrobial Chemotherapy · 2019 · 95 citations

, , +17