medRxiv · 2020 · 299 citations · 15 references
Veterinary MedicineInfectious Disease ControlInfectious DiseasesCommunicable Disease ControlDisease SurveillancePublic Health SurveillanceHospital SurveillanceOutbreak ControlPandemic PreparednessPandemic ResponsePublic Health ResponseSeasonal Transmission PatternsEpidemic ModelsHealthcare ResourcesHospital Capacity ManagementHospital Capacity UtilizationSars-cov-2 InfectionSeasonal VariationSocial Distancing BehaviorTransmission Intensity
Abstract The SARS-CoV-2 pandemic is straining healthcare resources worldwide, prompting social distancing measures to reduce transmission intensity. The amount of social distancing needed to curb the SARS-CoV-2 epidemic in the context of seasonally varying transmission remains unclear. Using a mathematical model, we assessed that one-time interventions will be insufficient to maintain COVID-19 prevalence within the critical care capacity of the United States. Seasonal variation in transmission will facilitate epidemic control during the summer months but could lead to an intense resurgence in the autumn. Intermittent distancing measures can maintain control of the epidemic, but without other interventions, these measures may be necessary into 2022. Increasing critical care capacity could reduce the duration of the SARS-CoV-2 epidemic while ensuring that critically ill patients receive appropriate care. Summary One-time distancing results in a fall COVID-19 peak. Intermittent efforts require greater hospital capacity and surveillance.
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Neil M. Ferguson, Daniel J. Laydon, G Nedjati Gilani et al. · Spiral (Imperial College London) · 2020 · 3.8K citations · Full text
Medicine, Infectious Disease Control, Infectious Diseases +13