[Epidemiological characteristics of confirmed COVID-19 cases in Tianjin].

Abstract

<b>Objective:</b> To investigate the clinical and epidemiological characteristics of 135 confirmed cases of COVID-19 in Tianjin. <b>Methods:</b> The clinical and epidemiological data of 135 cases of COVID-19 in Tianjin were collected, and the data were analyzed with descriptive method. The factors influencing the severity of the illness were analyzed. <b>Results:</b> Among the 135 COVID-19 cases, 72 were males and 63 were females, the age of the cases was (48.62±16.83) years, and the case fatality rate was 2.22%. Local transmission caused 74.81% of the cases. A total of 33 clusters occurred, involving 85.92% of all COVID-19 cases. The median of the incubation period of COVID-19 was 6.50 days, the average generation interval was 5 days, and the household secondary transmission rate was 20.46%. Fever was the main symptom (78.63%), followed by cough (56.48%). Multivariate regression analysis indicated that age (<i>OR</i>=1.038, 95%<i>CI</i>: 1.010-1.167) and the number of chronic underlying diseases (<i>OR</i>=1.709, 95%<i>CI</i>: 1.052-2.777) were the risk factors of severe illness. <b>Conclusions:</b> Fever was the main symptom at the early phase of COVID-19 in Tianjin, and the local cluster cases accounted for high proportion in confirmed COVID-19 cases reported in Tianjin. Severe illness was prone to occur in people with old age and multi underlying diseases. Strict isolation of close contacts and intensive care of high-risk groups are the main measures to reduce the morbidity and case fatality of COVID-19.