Publication | Open Access
A human monoclonal antibody blocking SARS-CoV-2 infection
287
Citations
18
References
2020
Year
Unknown Venue
VaccinationVaccine DevelopmentEmerging Infectious DiseasesMedicineHuman Monoclonal AntibodyVaccine TargetImmunologyCovid-19 PandemicVirologyHumoral ImmunityCommunal EpitopeViral ImmunityRespiratory DiseaseCovid-19
Abstract The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV). This cross-neutralizing antibody targets a communal epitope on these viruses and offers potential for prevention and treatment of COVID-19.
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