Concepedia

Publication | Closed Access

ICOS/ICOSL upregulation mediates inflammatory response and endothelial dysfunction in type 2 diabetes mellitus.

DOI

20

Citations

0

References

2018

Year

Zhang Hy, Ruan Lb, Li Y, Yang Tr, Wenjun Liu, Jiang Yx, Li Tr, Jinxing Quan, Wanling Xuan
PubMed

Abstract

HG and AGEs cause T cell inflammatory response and vascular endothelial dysfunction by upregulating ICOS/ICOSL, which may be one of the possible mechanisms of cardiovascular complications development in T2DM patients.